Sustainability | Flexbumin India

FLEXBUMIN^® has a low carbon footprint compared to glass bottles^7,13-15

FLEXBUMIN^®is the first carbon-certified,PLASMA DERIVED PRODUCT⁷

Requires less energy to manufacture^13,*
Uses less energy to transport^13,*
Is 90% lighter than glass, when empty^14,*
Reduces product waste^14,*
Reduces institutional disposal costs^13,*
Has 28% lower carbon footprint than albumin in glass^13,*

Substituting 4 FLEXBUMIN^® containers (100 mL) for 4 vials of Human Albumin (100 mL) each day for 1 year is equivalent to the CO₂ reduction gained from 70 trees grown from seedling to 10 years of age.¹³

^*100 mL FLEXBUMIN^® bag vs. 100 mL Human Albumin glass bottle

CERTIFIED BY THE CARBON TRUST.

FLEXBUMIN^® 25% CONTAINERS ARE CERTIFIED BY THE CARBON TRUST FOR REDUCTION IN CO2 EMISSIONS.¹⁶

LOWER CARBON FOOTPRINT^7,13-15

LIGHTER DISPOSAL WEIGHT^7,13-15

SAFE END-OF-LIFE DISPOSAL^7,13-15

REFERENCES

Flexbumin^® India Prescribing Information (PI).
Four-layer bag technology - Ref-35896- Baxter - May 2017.
Flexbumin^® latex free statement-Internal Memo-January 2020.
Analysis of Aluminum levels in Flexbumin^® during stability - Internal Memo - July 2014.
Efficiency Weights and Dimensions of Albumin vs. Flexbumin^® - Internal Memo - 2017
Maki DG, et al. Impact of Switching from an Open to a Closed Infusion System on Rates of Central Line-Associated Bloodstream Infection: A Meta-analysis of Time-Sequence Cohort Studies in 4 Countries. Infect Control Hosp Epidemiol 2011:32-50-58
Carbon Trust Certification letter-Ref-38783-November 2014.
Plasma Protein Therapeutics Association. Quality Standards of Excellence, Assurance and Leadership (QSEAL) Available at: https://www.pptaglobal.org/material/quality-standards-of-excellence-assurance-and-leadership-qseal Accessed May 2025.
Baxalta US Inc. Flexbumin^® 25%, Albumin (Human), USP, 25% Solution. Package insert. Jul 2017. Available at: https://www.shirecontent.com/PI/PDFS/FLEXBUMIN25_USA_ENG.pdf. Accessed November 2020.
Baxalta US Inc. Flexbumin^® 5%, Albumin (Human) USP, 5% Solution. Package insert. July 2017. Available at: https://www.shirecontent.com/PI/PDFS/FLEXBUMINS USA ENG.adf. Accessed November 2020.
Štrbová P, et al. Residual volumes and final weights in different types of plastic infusion containers. Int J Pharm Sci. 2016:8(3):293-296.
Summary Report of Observations for Flexbumin^® bags and Buminate bottles. Shire, Data on file-ID: FLEX-005. July 2017.
Albumin packaged as Flexbumin^® and BUMINATE. Baxter Healthcare Corporation. Data on file. 2012.
Disposal cost assessment. Baxter Healthcare Corporation. Data on file, ref-34896. April 2010.
DOW. Saran PVDC Resins & Films and the Environment, DOW Form No. 190-00500-0305 March 2005
The Carbon Trust Re-Certification. January 30, 2019.

FLEXBUMIN® has a low carbon footprint compared to glass bottles7,13-15

FLEXBUMIN®is the first carbon-certified,PLASMA DERIVED PRODUCT7

CERTIFIED BY THE CARBON TRUST.

FLEXBUMIN® 25% CONTAINERS ARE CERTIFIED BY THE CARBON TRUST FOR REDUCTION IN CO2 EMISSIONS.16

LOWER CARBON FOOTPRINT7,13-15

LIGHTER DISPOSAL WEIGHT7,13-15